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Optimal use of proton pump inhibitors for treating acid peptic diseases in primary care

Journal Volume 76 - 2013
Issue Fasc.4 - Case series
Author(s) J. Tack, E. Louis, V. Persy, D. Urbain
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(1) Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium ; (2) Gastroenterology, CHU and University of Liège, Liège, Belgium ; (3) Hugin Mugin Research, Antwerp, Belgium ; (4) Department of Gastroenterology, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

Heartburn, reflux and epigastric pain are frequently encoun- tered symptoms in primary care medicine. Acid peptic diseases such as peptic ulcer and gastrointestinal reflux disease have a high prevalence, can have important impact on patient quality of life and represent a considerable health care cost. Proton pump inhibi- tors (PPIs) are the most potent pharmacological inhibitors of gas- tric acid secretion currently available and are the mainstay medical therapy for acid peptic diseases. This review summarizes current evidence on treatment of acid- peptic diseases with proton pump inhibitors and provides primary care clinicians with best practice guidelines for optimal use of these drugs. (Acta gastroenterol. belg., 2013, 76, 393-402).

© Acta Gastro-Enterologica Belgica.
PMID 24592542